Full cycle of development and research of the effects of nanoparticles on tumor cells. Conducting a series of experiments on cellular structures similar to human structures, and later on living organisms in order to obtain dosage forms that can effectively be used to treat cancer.
The main vector of research is the study of the independent antitumor effects of nanoparticles. There is reason to believe that by modifying the surface of nanoparticles with active functional groups, it is possible to create a medicinal drug that has more capabilities than any of the currently existing means of treatment. Nanoparticles are currently most often considered solely as systems for drug delivery to targeted tumor cells. In this case, the nanoparticles themselves are barely involved in the processes of interaction of the drug with the tumor cells.
Recent studies indicate that there is immense interest in the creation of new systems that involve high levels of interaction of the drug with the surface of the nanoparticles. Experiments show that such systems enhance the action of anticancer chemotherapy and can change the configuration of the tumor cell membrane, thus opening access to the receptors and significantly reducing the dose of the chemotherapeutic agent.